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Creating knee cartilage

Japan Tissue Engineering of the Fujifilm group has commercialized regenerative medicine that comprises the transplantation of a patient’s cultured cells to restore damaged knee cartilage.

1.Significant damage to knee cartilage will not naturally heal

Knee pain is a common ailment, and some patients experience intense pain to the extent that it disrupts their daily routine. This is all the more troubling when knee cartilage is the cause. Treatments do exist to ease discomfort, but it is difficult at present to restore damaged knee cartilage to a healthy condition.

Cartilage tissue has no self-regenerating ability, so heavy damage will not naturally heal.

In light of this, Japan Tissue Engineering* of the Fujifilm group implemented a technology transfer from Professor Mitsuo Ochi of Hiroshima University to develop technology that creates autologous cultured cartilage for the first time in Japan.

*Japan Tissue Engineering Co., Ltd. is a subsidiary of FUJIFILM Corporation.

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2.Autologous cultured cartilage uses the patient’s own cells to repair knee cartilage

Cells are collected from 0.4 grams of the patient’s knee cartilage and cultured. After about four weeks, the autologous cultured cartilage is ready. When transplanted* to the patient, this restores the damaged cartilage and alleviates knee symptoms and pain, working toward a healthy state.

There should be no rejection, so once the autologous cultured cartilage stabilizes, the patient regains not only the ability to walk, but also to enjoy exercising. This will bring a smile back to the patient.

*Applicable conditions are traumatic cartilage defects or osteochondritis dissecans (cartilage defects of 4 square centimeters or more, excluding knee osteoarthritis).

3.A range of Fujifilm technologies that evolve regenerative medicine

Technology to process collagen and technology to control chemical reactions in the microscopic world—Fujifilm’s technologies cultivated in the field of photography are helping to evolve regenerative medicine such as with iPS cells.

Making regenerative medicine more commonplace.

Fujifilm is working to integrate its image analysis technology and other technologies cultivated in the field of photography to spread regenerative medicine.
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